From Germany:

Highway Munich-Innsbruck-Brenner-Sterzing-Bozen, take the exit marked South (Süd), then the Schnellstraße (MEBO) and continue until the exit Meran South (Süd). From here, follow the signs Jaufenpaß/Timmelspass/Passeiertal to Quellenhof

Variation: Brenner exit, then Sterzing-Jaufenpass-Passeiertal. Please note that the Jaufenpassübergang is at an altitude of 2000 m, and can be very winding and narrow at times. For this reason, we do not recommend this route if the weather and road conditions are bad.

Highway (A7) to Kempten-Reute-Imst-Landeck-Reschenpass-Meran, take the exit marked South (Süd), then follow the signs Jaufenpass/Timmelspaß/Passeiertal to Riffian, Passeiertal and finally to Quellenhof. (You do not need a road tax sticker for the highway (called a Vignette) if you take the national highway (Bundesstraße) from Imst to Landeck).

Variation: Kempten-Reute-Ötztal-Timmelsjochpass to Passeiertal. Timmelsjoch is only open from June to mid-October (because it lies at an altitude of 2500 m, it is closed at this time due to snow). For this reason, we do not recommend this route if the weather and road conditions are bad. (You do not need a road tax sticker for this route; however, there is one toll fee along the way).

From Switzerland:

From Switzerland, follow the signs Ofenpaß-Münstertal-Glurns-Schluderns-Meran and take the exit South (Süd), then follow the signs Jaufenpass/Timmelspaß/Passeiertal.